Upstream Development Scientist


About this role

Brunel has a great opportunity to support our client who is a multinational pharmaceutical company.

They are in full growth mode and are seeking a Upstream development Scientist. This is an onsite role supporting the Toronto location. This is an exciting 12 month contract opportunity.

This role is in house supporting the Toronto location. This is a 1 year contract opportunity with a possibility of extension.

  • Development of new vaccine processes
  • Partially based within the upstream development platform of BRD to assist with development of MenB upstream processes, including cell expansion, fermentation, and recovery.
  • Provide feedback during the development process to ensure that the new process is compatible with CMP capabilities and transferable to GMP production.
  • Assist with the preparation of reports summarizing experimental and assay results to be disseminated to supervisor and external customers.
  • Technology transfer of new processes into and out of CMP
  • Support the transfer and / or implementation of new technologies / equipment / processes for MenB upstream process, which is transferred from the Upstream into the CMP
  • GMP production of clinical drug substances
  • Support GMP production of the Men B Clinical Drug Substance in CMP facilities. This includes use of fermentation and recovery processing equipment, including disposable closed systems for upstream processing.
  • This also includes understanding and performance of environmental monitoring within g Class C areas, as well as maintaining records for inventory of materials. Cross train and support other production areas as needed.
  • Preparation of documents & GMP compliance activities
  • Assist with preparation of SOPs, master BPRs, & validation protocols.
  • Assist with preparation of Manufacturing Record Files (MRFs).
  • Document development experiments in laboratory notebooks and assist with preparation of summary reports. Help to maintain inventories through tracking, cycle counting, forecasting and ordering


Bachelor’s degree in Science

Previous experience within a similar capacity


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  • Certifications (optional)
  • Job references (optional)
  • Motivation Letter (optional)
  • Resume
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Any questions remaining?

Your consultant, Martin van Helden is happy to clarify anything about this vacancy. When reaching out, use the pub number:

Account manager

Martin van Helden
Brunel Canada - Toronto

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